Is there a connection between eczema and constipation？
Eczema, also known as atopic dermatitis, is caused by inflammation and dysfunction of the skin barrier, which results in dehydration, itching, and irritation. Frequently, the symptoms of eczema extend beyond the surface. Inflammation associated with eczema can cause or be caused by other conditions affecting various organs in the body.
In particular, a growing body of research has uncovered the gut-skin axis, a close relationship between the digestive tract and the epidermis. When this axis is disturbed, the health of both symptoms may be compromised. Consequently, some eczema sufferers may also experience digestive issues, such as constipation.
Eczema and constipation
In a study involving more than 170,000 Taiwanese participants, those with constipation were more than twice as likely to have eczema as those without constipation. However, it is unclear whether eczema patients are more susceptible to constipation.
Eczema and gut health
The epidermis and intestinal lining serve as the body's first line of defense against allergens and pathogens in the environment. Every day, both the epidermis and the intestinal lining are exposed to billions of microbes.
When the barrier between the inside and outside is compromised, as in eczema, pathogens and allergens can cause inflammation, irritation, and other symptoms.
The same phenomenon can occur in the intestines. Changes in the gut microbiome — the collection of bacteria and viruses residing in the digestive tract — as well as inflammation and irritation in the gut membrane can both cause and result in constipation.
These two factors can compromise the epithelial barrier in the digestive tract, exposing the body to allergens and microorganisms. A "leaky gut" can induce inflammation throughout the body, including the skin.
Similarly, eczematous skin inflammation can affect other organs and extend throughout the body. Inflammatory molecules and immune cells can circulate in the circulation and affect the digestive system, causing inflammation that can negatively impact gut health.
Managing eczema and constipation
Food sensitivities and allergies are prevalent in eczema patients. In some instances, in addition to skin symptoms, these sensitivities may also result in digestive issues. Consequently, many individuals believe that elimination diets that exclude common food allergens can universally alleviate eczema symptoms in both the skin and the intestines.
If a person has both psoriasis and constipation, their healthcare team can assist them in managing their symptoms through lifestyle modifications and medication. A physician may recommend a multidisciplinary approach that includes both a gastroenterologist and a dermatologist. Some eczema medications can cause digestive problems, so a dermatologist can also help adjust medications if necessary.
Summary
The health of the skin and the gastrointestinal tract are closely linked, and individuals with digestive issues such as constipation may be more likely to develop skin conditions such as eczema.
With the assistance of a gastroenterologist, an eczema patient's dermatologist may be able to provide alleviation through lifestyle modifications and medication.
資料來源：Morgan Meissner, PhD (2023), “Is there a connection between eczema and constipation? ”. Medical News Today. https://www.medicalnewstoday.com/articles/eczema-and-constipation